Apr 6, 2012

Histopathology slides - Mucinous tumour of ovary

Mucinous tumours of ovary

Mucinous tumours of the ovary may be benign or malignant. The benign cystadenoma has a characteristically smooth outer surface composed of the ovarian capsule. The cystic locules are filled with mucin and lined by tall columnar epithelium with uniform basal nuclei and copious mucin-containing cytoplasm at the luminal aspect. These cells are thought to resemble endocervical epithelial cells.
   The malignant variant, mucinous cystadenocarcinoma, is less common. The tumou is more solid, with smaller cystic spaces. The cells are usually recognisably columnar, but the nuclei are larger and more pleomorphic. The cells are crowded and show increased mitotic activity. Evidence of malignancy is usually demonstrated by invasion of tumour cells into the supporting stroma.
   Some mucinous tumours show many of the cytological features of mucinous adenocarcinoma without actual invasion of the stroma. These are called borderline or atypically proliferating mucinous tumours and their prognosis is better than for overtly malignant tumours.

[P/S: you gave me so many pictures of mucinous tumour, what for la... =.=]

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